Non-invasive delivery of non-steroidal drugs
PI: Prof. Rohit Srivastava, Biosciences and Bioengineering
Tata Fellow: Shwetha Hymavathi (2014-16)

This project proposes to develop an affordable non-invasive drug delivery system to administer pain relieving drugs for a prolonged period of time without any requirement for human intervention in patients suffering from rheumatoid arthritis or osteoarthritis. The system would deliver the drug directly to the desired area and would maintain the drug level in therapeutic range unlike administration via oral or injectable devices, which cause the drug levels to over or under shoot the required therapeutic range thereby making our system to have higher efficiency than the conventional systems. Since our intended system does not cause any overshoot or undershoot in the administered drug level, a comparatively a lesser amount of drug may be effective at par with doses required in conventional methods. The system would be non-invasive which makes it less prone to infections caused by invasive methods. The system would maintain the level for prolonged time duration eliminating the need for frequent oral administration. It would serve as an alternate treatment for patients with osteoarthritis or rheumatoid arthritis in which oral medications and/or surgery are not options or are ineffective.