Monitoring of neonatal jaundice, a highly prevalent condition in newborns, requires frequent monitoring of bilirubin levels. Monitoring is done through an invasive technique, which is potentially infectious. Blood tests also lead to longer diagnostic procedures, and require lab infrastructure. Alternative non-invasive measurement devices for jaundice are extremely expensive, and practically unavailable outside of the high resource private healthcare settings. Using the multi-spectral imaging technique, we have developed the Biliscope which can estimate the amount of bilirubin, and remove confounding effects of skin tone, blood flow etc. The handheld device can be combined with a mobile app which supports a one-touch workflow, to report a relative hyperbilirubin measurement, on an NICU-friendly interface.